ATOM 2

During the Atom 1 project, 4 industrial partners and 4 academic partners studied a number of selected industrially relevant processes for their applicability in flow, in an attempt to make the challenging step from proof of concept at the lab scale to trial runs at the kilo scale. Key lessons learnt during this 2-years project include dealing with solid-liquid heterogeneous feed streams, viscosity change during the reaction and mass transfer limitations in liquid-liquid heterogeneous systems. Importantly, the encouraging results obtained were all on processes that are economically very relevant to the industrial partners. 

The partners wish to continue this effort in a similar manner. 4 large industrial partners are involved, two with an interest in GMP manufacturing, and two with an interest in non-GMP manufacturing. The goal of Atom-2 is to build further upon the results accomplished in Atom-1. We wish to ensure an instream of relevant processes to be studied at lab scale and then to be scaled up to kilo scale. It is the intention of Atom-2 to take an additional step in complexity of the processes studied. On the other hand, we wish to get one step closer to industrialization, hence there will be a larger emphasis on the further scale up beyond the kilogram scale and on engineering aspects of a (pilot) production installation.